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Bedaquiline Fumurate

Bedaquiline Fumurate

【Chemical Name】Bedaquiline Fumurate

【Original】Johnson

【Time to market】2012.12.28

【Dosage and Usage】Tablets: 20 mg,100 mg. used for the treatment of adult and pediatric patients

  (5 years and older and weighing at least 15 kg) with pulmonary multi-drug resistant tuberculosis       (MDR-TB).


Bedaquiline Fumarate

一、 Product Overview

Bedaquiline Fumarate,developed by Johnson, is a diarylquinoline antimycobacterial drug indicated as part of combination therapy in adult and pediatric patients (5 years and older and weighing at least 15 kg) with pulmonary multi-drug resistant tuberculosis (MDR-TB).It was approved by FDA on Dec. 28, 2012.


二、Main products

Description

Structural Formula

CAS No.

Category

Bedaquiline Fumarate

MS1036-01 845533-86-0.bmp

845533-86-0

API

N-(4-Bromo-phenyl)-3-phenyl-propionamide

MS1036-05 316146-27-7.bmp

 316146-27-7

intermediates

3-benzyl-6-bromo-2-chloroquinoline 

MS1036-04 654655-68-2.bmp

654655-68-2

intermediates

3-benzyl-6-bromo-2-methoxyquinoline

MS1036-02 654655-69-3.bmp

654655-69-3

intermediates

3-(dimethylamino)-1-(naphthalen-1-yl)propan-1-one   hydrochloride

MS1036-03 5409-58-5.bmp

5409-58-5

intermediates

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